Database Authors
Ron Caspi1, Carol A Fulcher1, Anamika Kothari1, Markus Krummenacker1, Amanda Mackie2, Lisa Moore1, Suzanne Paley1, Pallavi Subhraveti1, Austin Swart1, Peter D Karp1
1SRI International, 2Macquarie University
See all credits, including past contributors.
Summary MetaCyc is a curated multi-organism database of experimentally elucidated metabolic pathways from all domains of life.

MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated metabolites, reactions, enzymes, and genes. The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway.

See the MetaCyc home page for more information.

Database Contents
Genes16,536
Pathways3,691
Enzymatic Reactions20,367
Transport Reactions1,065
Polypeptides18,325
Protein Complexes5,110
Enzymes14,660
Transporters725
Compounds20,618
tRNAs8
Growth Media19
Protein Features37,499
GO Annotations77,741
Database Version30.0 [History of Updates]
Image of mugs with the MetaCyc logo, featuring the caffeine biosynthesis pathway
The MetaCyc mug, featuring the caffeine biosynthesis pathway. This mug and others are available for purchase at the BioCyc mug shop.
Copyright © SRI International 1999-2026, Marine Biological Laboratory 1998-2001, DoubleTwist Inc 1998-1999. All Rights Reserved.

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
Page generated by Pathway Tools version 30.0 (software by SRI International) on Wed Aug 26, 2026, BIOCYC15.