Database Authors
Ron Caspi1, Carol A Fulcher1, Anamika Kothari1, Markus Krummenacker1, Amanda Mackie2, Lisa Moore1, Suzanne Paley1, Pallavi Subhraveti1, Austin Swart1, Peter D Karp1
1SRI International, 2Macquarie University
See all credits, including past contributors.
Summary MetaCyc is a curated multi-organism database of experimentally elucidated metabolic pathways from all domains of life.

MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated metabolites, reactions, enzymes, and genes. The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway.

See the MetaCyc home page for more information.

Database Contents
Genes16,325
Pathways3,653
Enzymatic Reactions20,093
Transport Reactions1,042
Polypeptides18,141
Protein Complexes5,055
Enzymes14,506
Transporters714
Compounds20,380
tRNAs8
Growth Media19
Protein Features36,883
GO Annotations83,510
Database Version29.5 [History of Updates]
Image of mugs with the MetaCyc logo, featuring the caffeine biosynthesis pathway
The MetaCyc mug, featuring the caffeine biosynthesis pathway. This mug and others are available for purchase at the BioCyc mug shop.
Copyright © SRI International 1999-2024, Marine Biological Laboratory 1998-2001, DoubleTwist Inc 1998-1999. All Rights Reserved.

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
Page generated by Pathway Tools version 29.5 (software by SRI International) on Sat Feb 7, 2026, BIOCYC15A.